I CONGRESO DIGITAL AEP. Libro de comunicaciones y casos clínicos

496 ISBN: 978-84-09-24491-1 ÁREA DE ESPECIALIDAD • INFECTOLOGÍA ASOCIACIÓN ESPAÑOLA DE PEDIATRÍA BIRTH START OF HAART ONE YEAR OF HAART C1 (n = 16) ¹ C2 (n = 31) ² Total (n = 47) C1 (n = 16) ¹ C2 (n = 31) ² Total (n = 47) C1 (n = 16) ¹ C2 (n = 31) ² Total (n = 47) LAZ/HAZ³ , mean (SD) p -value -0.91 (1.13) -0.47 (1.25) -0.67 (1.20) p = 0.313 5 -0.68 (1.33) -0.94 (0.91) -0.85 (1.06) p = 0.443 5 -0.05 (0.93) -0.97 (0.93) -0.66 (1.07) p = 0.04 5 High height  % (n) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 6.25 (1) 0 (0) 2.13 (1) RR (CI) ? ? ? ? ? ? Normal height % (n) 81.25 (13) 70.97 (22) 74,47 (35) 87.50 (14) 90.32 (28) 89.36 (42) 87.50 (14) 70.97 (22) 76.59 (36) RR (CI) 1.49 (0.51 - 4.33) 0,83 (0.26- 2.65) 2.14  (0.57 - 8.00) Low height  % (n) 18.75 (3) 29.03 (9) 25.53 (12) 12.50 (2) 9.68 (3) 10.64 (5) 6.25 (1) 29,03 (9) 21.28 (10) RR (CI) 0.67  (0.23 - 1.96) 1.20  (0.38 - 3.81) 0.25  (0.04 - 1.65) WAZ4, mean (SD) p -value -0.12 (0.43) -0.21 (0.35) -0.07 (0.39) p = 0.630 5 -1.05 (1.2) - 0.47 (0.79) -0.67 (0.98) p = 0.052 5 -0.65 (1.06) -0.47 (1.08) - 0.53 (0.84) p = 0.498 5 Overweight  % (n) 0 (0) 0 (0) 0 (0) 6.25 (1) 3.23 (1) 4.26 (2) 6.25 (1) 0 (0) 2.13 (1) RR (CI) ? ? 1.94  (0.13 - 28.99) ? ? Normal weight % (n) 100 (16) 100 (31) 100 (47) 68.75 (11) 87.09 (27) 80.85 (38) 75.00 (12) 93.55 (29) 87.23 (41) RR (CI) ? ? 0.52  (0.24 - 1.12) 0.44 * (0.21 - 0.92) Underweight  % (n) 0 (0) 0 (0) 0 (0) 25 (4) 9.68 (3) 14.89 (7) 18.75 (3) 6.45 (2) 10.64 (5) RR (CI) ? ? 1.90  (0.86 - 4.22) 1.94  (0.83 - 4.52) TWO YEARS OF HAART LAST CONTROL AVAILABLE C1 (n = 16) ¹ C2 (n = 31) ² Total (n = 47) C1 (n = 16) ¹ C2 (n = 31) ² Total (n = 47) LAZ/HAZ³ , mean (SD) p -value - 0.08 (1.03) -0.88 (1.15) -0.61 (1.16) p = 0.024 5 -0.59 (1.05) -0.42 (1.06) -0.48 (1.05) p = 0.528 5 High height  % (n) 0 (0) 3.23 (1) 2.13 (1) 0 (0) 0 (0) 0 (0) RR (CI) ? ? ? ? Normal height % (n) 93.75 (15) 64,51 (20) 74,47 (35) 87.5 (14) 87.1 (27) 87.23 (41) RR (CI) 1.45* (1.09 - 1.94) 1.02  (0,31 - 3,43) Low height  % (n) 6.25 (1) 32,26 (10) 23.40 (11) 12.5 (2) 12.9 (4) 12.77 (6) RR (CI) 0.22 (0.03 - 1.47) 0.98  (0.29 - 3.27) WAZ4, mean (SD) p -value -0.42 (1.10) -0.40 (0.82) -0.41 (0.91) p = 0.936 5 -0.15 (1.07) -0.33 (1.32) -0.27 (1.23) p = 0.673 5 Overweight  % (n) 0 (0) 3.23 (1)  2.13 (1) 6.25 (1) 9.68 (3) 8.51 (4) RR (CI) ? ? 0.72  (0.13 - 4.10) Normal weight % (n) 75 (12) 93.54 (29) 87.23 (41) 93.75 (15) 87.09 (27) 89.36 (42) RR (CI) 0.44 * (0.21 - 0.92) 1.79 (0.30 - 10.80) Underweight  % (n) 25 (4) 3.23 (1)  10.64 (5) 0 (0) 3.23 (1) 2.13 (1) RR (CI) 2.80 * (1.46 - 5.36) ? ? Growth outcomes with regard to HAART starting age.Lenght/Height-for-age-Z-score (LAZ/HAZ) and Weight-for-age-Z-score (WAZ) in the cohorts were compared at birth, at the time of starting HAART, at one and two years of having started HAART and at the last medical control available. Relative risk (RR) for LAZ/HAZ and WAZ were also calculated for normal height, high height, low height, normal weight, overweight and lowweight, respectively.Notes: Theheight andweight of bothgroupswere assessedandexpressedas age- and sex-adjustedZ scores, basedonWHOReference childgrowth standards. According toWHO references parameters of height, a Z-score between -1.5 and 2was considered normal height, a Z-score = 2 high height for and a Z-score = -1.5 lowheight. Weight was also evaluated withWHO references parameters of weigh. Normal weight was defined by a Z-score between -1.5 and 2, overweight when Z-score was = 2 and underweight, Z-score = 1.5. For Z-scores means and standard deviations are presented. For quantitative variables means and standard deviations (SD) values are presented. For qualitative variables frequencies (n) and proportions (%) are presented. ¹C1 when HAARTwas introduced before turning 12months of age. ²C2 when HAARTwas started at 12months of age or after. ³Lenght/Height-for-age-Z-score. 4Weight-for-age-Z-score. 5Two-sided Student t were used for difference in means for HAZ and WAZ. ? Used when the calcul of relative risk was not required. * Used to remark when the relative risk is statistically different.